A multinational survey of physician knowledge about management of chronic hepatitis C

Abstract

Introduction and objectives: Up-to-date knowledge of hepatitis C virus (HCV) management among healthcare providers is crucial for improving patient outcomes. This study evaluates physicians' awareness, attitudes, self-efficacy, perceptions, and barriers related to current HCV management guidelines and post-treatment follow-up.

Materials and methods: We invited healthcare providers treating HCV patients to complete a 48-question survey regarding their practices, guideline familiarity, and related attitudes.

Results: The survey was completed by 183 physicians from 8 countries, including hepatologists (32 %), gastroenterologists (39 %), internal medicine specialists (12 %), and infectious disease specialists (16 %). The majority (95 %) were aware of at least one treatment guideline, with the EASL guideline cited by 84 % and the AASLD guideline by 72 %. Most (94 %) believed post-HCV treatment follow-up was effective for detecting complications, and 93 % recommended continued follow-up. Although 90 % felt well-informed about guidelines, 39 % reported encountering inconsistencies. Sixty-one percent recognized that HCV elimination reduces the rate of decompensation but does not abolish the risk of hepatocellular carcinoma (HCC). Overall, 86 % acknowledged the need for follow-up in patients who achieved sustained virological response (SVR), with the most commonly recommended intervals being six months for non-cirrhotic patients and three months for cirrhotic patients. Minimal barriers to follow-up were reported, with only 1.6 % to 4.4 % not discussing its benefits due to time or resource constraints.

Conclusions: The surveyed physicians demonstrated a strong awareness of the current HCV guidelines but indicated potential gaps in knowledge and inconsistencies. Continuous education and support are essential to enhance adherence to HCV management protocols.

Keywords: Adherence; Cirrhosis; DAAs; Guidelines; HCC; HCV; Knowledge; SVR.