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Case Reports
. 2025 Aug 14;5(4):100550.
doi: 10.1016/j.xagr.2025.100550. eCollection 2025 Nov.

Monkeypox virus infection in a 23-year-old woman with a genital rash and global skin lesions: evidence for spouse-to-spouse transmission

Wen-Shuang Li  1 , Rong-Jing Dong  2 , Shui-Tao Yi  1 , Ru-Qin Zhang  1 , Rui-Xia Chen  1 , Yan-Jie Ning  1 , Dian-Jiang Xiao  1
Affiliations
Case Reports

Monkeypox virus infection in a 23-year-old woman with a genital rash and global skin lesions: evidence for spouse-to-spouse transmission

Wen-Shuang Li et al. AJOG Glob Rep. .

Abstract

We report one case in China of a couple simultaneously infected with the monkeypox. Both spouses developed genital skin lesions successively and the female partner had widespread skin lesions all over her body, while the male partner is HIV-positive, had a history of homosexual behavior before the onset of symptoms.

Keywords: Monkeypox Virus; Woman genital rash; global skin lesions; spouse-to-spouse transmission.

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Figures

Figure
Figure
The systemic skin manifestation during monkeypox infection in a young woman in Yunnan, China before treatment (A, B, and C) and after treatment (D).
See this image and copyright information in PMC

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