Retraction Note: Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells

Yuying Liu^#^{1

2}, Xiaoyu Liang^#¹, Xiaonan Yin^#¹, Jiadi Lv¹, Ke Tang³, Jingwei Ma³, Tiantian Ji³, Huafeng Zhang¹, Wenqian Dong¹, Xun Jin¹, Degao Chen¹, Yanchun Li¹, Songyan Zhang⁴, Heidi Q Xie⁴, Bin Zhao⁴, Tong Zhao⁵, Jinzhi Lu¹, Zhuo-Wei Hu⁶, Xuetao Cao¹, F Xiao-Feng Qin^{7

8}, Bo Huang^{9

10

11}

Affiliations

¹ National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 100005, Beijing, China.
² Clinical Immunology Center, Chinese Academy of Medical Sciences, 100005, Beijing, China.
³ Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, 430030, Wuhan, China.
⁴ State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 100085, Beijing, China.
⁵ Institute of Microbiology, Chinese Academy of Sciences, 100101, Beijing, China.
⁶ Molecular Immunology and Pharmacology Group, State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China.
⁷ Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, 100005, Beijing, China.
⁸ Suzhou Institute of Systems Medicine, 215123, Suzhou, China.
⁹ National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 100005, Beijing, China. tjhuangbo@hotmail.com.
¹⁰ Clinical Immunology Center, Chinese Academy of Medical Sciences, 100005, Beijing, China. tjhuangbo@hotmail.com.
¹¹ Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, 430030, Wuhan, China. tjhuangbo@hotmail.com.

^# Contributed equally.

PMID: 41057331
PMCID: PMC12504444
DOI: 10.1038/s41467-025-64654-x

Retraction Note: Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells

Yuying Liu et al. Nat Commun. 2025.

. 2025 Oct 7;16(1):8888.

doi: 10.1038/s41467-025-64654-x.

Authors

Affiliations

¹ National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 100005, Beijing, China.
² Clinical Immunology Center, Chinese Academy of Medical Sciences, 100005, Beijing, China.
³ Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, 430030, Wuhan, China.
⁴ State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 100085, Beijing, China.
⁵ Institute of Microbiology, Chinese Academy of Sciences, 100101, Beijing, China.
⁶ Molecular Immunology and Pharmacology Group, State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China.
⁷ Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, 100005, Beijing, China.
⁸ Suzhou Institute of Systems Medicine, 215123, Suzhou, China.
⁹ National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 100005, Beijing, China. tjhuangbo@hotmail.com.
¹⁰ Clinical Immunology Center, Chinese Academy of Medical Sciences, 100005, Beijing, China. tjhuangbo@hotmail.com.
¹¹ Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, 430030, Wuhan, China. tjhuangbo@hotmail.com.

^# Contributed equally.

PMID: 41057331
PMCID: PMC12504444
DOI: 10.1038/s41467-025-64654-x

No abstract available

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Retraction of

Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells.
Liu Y, Liang X, Yin X, Lv J, Tang K, Ma J, Ji T, Zhang H, Dong W, Jin X, Chen D, Li Y, Zhang S, Xie HQ, Zhao B, Zhao T, Lu J, Hu ZW, Cao X, Qin FX, Huang B. Liu Y, et al. Nat Commun. 2017 May 10;8:15207. doi: 10.1038/ncomms15207. Nat Commun. 2017. Retraction in: Nat Commun. 2025 Oct 7;16(1):8888. doi: 10.1038/s41467-025-64654-x. PMID: 28488695 Free PMC article. Retracted.

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Retraction Note: Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells

Affiliations

Retraction Note: Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells

Authors

Affiliations

Retraction of

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