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. 2025 Oct 9.
doi: 10.1097/SCS.0000000000011974. Online ahead of print.

Pharyngeal Arches, Chapter 3: Craniofacial Syndromes

Affiliations

Pharyngeal Arches, Chapter 3: Craniofacial Syndromes

Nicole C Episalla et al. J Craniofac Surg. .

Abstract

Pharyngeal arch development is complex and can result in a wide range of unique head and neck anomalies. Understanding the developmental processes and the related pathoanatomy is essential for clinicians who manage affected patients. This manuscript is the third in a 4-part educational series for plastic surgeons focusing on normal and abnormal pharyngeal arch development. A summary of the etiology and clinical features of each syndrome covered in this manuscript is provided in the Supplemental Table, Supplemental Digital Content 1, http://links.lww.com/SCS/I489 for quick reference.

Keywords: Congenital anomalies; Robin sequence; craniofacial syndromes; pharyngeal arches.

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Conflict of interest statement

The authors report no conflicts of interest.

References

    1. Prows CA, Bender PL. Beyond Pierre Robin sequence. Neonatal Netw 1999;18:13–19
    1. CÔté A, Fanous A, Almajed A, et al. Pierre Robin sequence: review of diagnostic and treatment challenges. Int J Pediatr Otorhinolaryngol 2015;79:451–464
    1. Cladis F, Kumar A, Grunwaldt L, et al. Pierre Robin sequence: a perioperative review. Anesth Analg 2014;119:400–412
    1. Chocron Y, Alabdulkarim A, Czuzoj-Shulman N, et al. Incidence, characteristics, and outcomes of Robin sequence: a population-based analysis in the United States. J Craniofac Surg 2024;35:6–9
    1. Giudice A, Barone S, Belhous K, et al. Pierre Robin sequence: a comprehensive narrative review of the literature over time. J Stomatol Oral Maxillofac Surg 2018;119:419–428

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