Premorbid Metabolic Syndrome Is Associated with the Hypoinflammatory Phenotype in Acute Respiratory Distress Syndrome and Sepsis

Avery M Bogart^{1

2}, Sarah N Obeidalla³, Rombout B E van Amstel⁴, Olaf Cremer^{4

5}, Lieuwe D J Bos⁴, Brian Bartek⁶, Pratik S Sinha⁶, Carolyn S Calfee^{7

8}, V Eric Kerchberger^{9

3}, Lorraine B Ware^{1

3}; MARS Consortium

Collaborators, Affiliations

¹ Department of Pathology, Microbiology, and Immunology.
² Vanderbilt University School of Medicine, Nashville, Tennessee.
³ Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
⁴ Department of Intensive Care Medicine, Amsterdam University Medical Center, Locatie Amsterdam Medical Center, Amsterdam, the Netherlands.
⁵ Department of Intensive Care, University Medical Center Utrecht, Utrecht, the Netherlands.
⁶ Division of Clinical and Translational Research, Department of Anesthesia, Washington University in St Louis, St. Louis, Missouri; and.
⁷ Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine and.
⁸ Department of Anesthesia, University of California, San Francisco, San Francisco, California.
⁹ Department of Biomedical Informatics, and.

Avery M Bogart et al. Am J Respir Crit Care Med. 2025 Dec.

. 2025 Dec;211(12):2399-2401.

doi: 10.1164/rccm.202503-0596RL.

¹ Department of Pathology, Microbiology, and Immunology.
² Vanderbilt University School of Medicine, Nashville, Tennessee.
³ Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
⁴ Department of Intensive Care Medicine, Amsterdam University Medical Center, Locatie Amsterdam Medical Center, Amsterdam, the Netherlands.
⁵ Department of Intensive Care, University Medical Center Utrecht, Utrecht, the Netherlands.
⁶ Division of Clinical and Translational Research, Department of Anesthesia, Washington University in St Louis, St. Louis, Missouri; and.
⁷ Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine and.
⁸ Department of Anesthesia, University of California, San Francisco, San Francisco, California.
⁹ Department of Biomedical Informatics, and.

No abstract available

Publication types