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Review
. 2025 Oct 13;29(7-8):104752.
doi: 10.1016/j.canrad.2025.104752. Online ahead of print.

Radiotherapy for endometrial cancer: 2025 update

Cyrus Chargari  1 , Anne Ducassou  2 , Julie Leblanc  3 , François Lucia  4 , Adeline Petit  5 , Isabelle Flandin  6 , Abel Cordoba  7 , Caroline Lafond  8 , Sophie Renard  9 , Alexandre Escande  10
Affiliations
Review

Radiotherapy for endometrial cancer: 2025 update

Cyrus Chargari et al. Cancer Radiother. .

Abstract

The first intent upfront treatment of endometrial cancer is surgery. External radiotherapy and brachytherapy, however, are important tools in adjuvant setting, according to histopathological risk factors for locoregional recurrence or in the event of an inoperable tumour. We present the 2025 update of the recommendations of the Société française de radiothérapie oncologique (SFRO; French society of radiation oncology) on the indications and technical methods of performing radiotherapy and brachytherapy for endometrial cancer.

Keywords: Brachytherapy; Cancers de l’endomètre; Cancers de l’utérus; Curiethérapie; Endometrial cancer; Guidelines; Image-guided radiotherapy; Radiation therapy; Radiothérapie; Radiothérapie guidée par l’imagerie; Recommandations; SFRO; Société française de radiothérapie oncologique.

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Conflict of interest statement

Disclosure of interests CC reports personal fees and nonfinancial support from MSD, EISAI, GSK, Merck, Bayer, AstraZeneca and service as an investigator for clinical trials sponsored or supported by TherAgulX and Roche. The other authors did not disclose their relationships/activities/interests.

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