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Review
. 2025 Oct;24(10):e70480.
doi: 10.1111/jocd.70480.

The Whys and Hows of Aesthetic Medicine: Anamnesis, Skin Assessment and Instrumental Evaluation by A Specific, Update Protocol (Mediskin Check-Up)

Affiliations
Review

The Whys and Hows of Aesthetic Medicine: Anamnesis, Skin Assessment and Instrumental Evaluation by A Specific, Update Protocol (Mediskin Check-Up)

E Bartoletti et al. J Cosmet Dermatol. 2025 Oct.

Abstract

Background: Skin evaluation in Aesthetic Medicine requires standardized methods to ensure reproducibility. The Mediskin check-up protocol, first introduced in the late 1970s, provided a systematic approach to skin assessment in non-pathological contexts. Advances in medicine and cosmetology have since required an update of this methodology.

Aims: To present the updated Mediskin check-up protocol and demonstrate its value for accurate diagnosis and personalized treatment planning in Aesthetic Medicine.

Patients/methods: The revised protocol integrates updated anamnesis, clinical examination, and instrumental evaluation under standardized conditions to ensure reproducibility.

Results: The protocol allows for the identification of skin biotypes (normal, seborrheic, dry, or sensitive), defined by combined anamnesis, clinical findings, and instrumental parameters. It establishes a reproducible diagnostic framework that supports follow-up assessments and individualized treatment regimens.

Conclusions: The updated Mediskin protocol provides a standardized and reproducible method for skin evaluation in Aesthetic Medicine. By integrating clinical and instrumental data, it enhances diagnostic accuracy, guides personalized therapy, and supports safe and effective patient care.

Keywords: Mediskin check‐up; aesthetic medicine; cosmetic schedule; instrumental skin evaluation; skin biotype; standardization.

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Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Arda O., Göksügür N., and Tüzün Y., “Basic Histological Structure and Functions of Facial Skin,” Clinical Dermatology 32, no. 1 (2014): 3–13, 10.1016/j.clindermatol.2013.05.021. - DOI - PubMed
    1. Zargaran D., Zoller F., Zargaran A., Weyrich T., and Mosahebi A., “Facial Skin Ageing: Key Concepts and Overview of Processes,” International Journal of Cosmetic Science 44, no. 4 (2022): 414–420, 10.1111/ics.12779. - DOI - PMC - PubMed
    1. Alexander H., Brown S., Danby S., and Flohr C., “Research Techniques Made Simple: Transepidermal Water Loss Measurement as a Research Tool,” Journal of Investigative Dermatology 138, no. 11 (2018): 2295–2300.e1, 10.1016/j.jid.2018.09.001. - DOI - PubMed
    1. Ramette G. and Bartoletti C. A., “Check‐Up Cutaneo in Medicina Estetica,” La Medicina Estetica 7, no. 2 (1983): 65–70.
    1. Bartoletti C. A., “Dossier dermo‐cosmetologico per un check‐up cutaneo secondo il protocollo di Bartoletti e Ramette (Mediskin check up),” La Medicina Estetica 13, no. 1 (1989): 1–14.

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