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. 1972 Mar 10;175(4026):1126-8.
doi: 10.1126/science.175.4026.1126.

Thymus-derived lymphocytes: humoral and cellular reactions distinguished by hydrocortisone

S Segal, I R Cohen, M Feldman

Thymus-derived lymphocytes: humoral and cellular reactions distinguished by hydrocortisone

S Segal et al. Science. .

Abstract

Lymphocytes derived from the thymus (T cells) take part in the induction of humoral antibody and also effect cell-mediated graft-versus-host reactions. Preliminary treatment of mice with hydrocortisone caused an inhibition of T-cell function in humoral immunity, while enhancing the graft-versus-host reactivity of the same population of spleen cells. This suggests that different types of T cells participate in cellular and humoral immune reactions.

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