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Case Reports
. 2025 Nov;41(11):2277-2278.
doi: 10.1007/s10554-025-03516-5. Epub 2025 Oct 17.

Giant cell myocarditis in a middle-aged male: features in CMR

Jerald Garvin Lim  1 , Carole Dennie  2 , Suman Prabhakar  2
Affiliations
Case Reports

Giant cell myocarditis in a middle-aged male: features in CMR

Jerald Garvin Lim et al. Int J Cardiovasc Imaging. 2025 Nov.

Abstract

Giant cell myocarditis (GCM) is a rare, rapidly progressive inflammatory cardiomyopathy that often presents with fulminant heart failure. We report a 52-year-old male with acute chest pain and cardiogenic shock, with cardiac MRI and biopsy confirming GCM. Early recognition and timely immunosuppressive therapy were critical to management and improving clinical outcomes.

Keywords: Cardiac MRI; Cardiogenic shock; Endomyocardial biopsy; Giant cell myocarditis; Late Gadolinium enhancement; Multiparametric mapping.

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Conflict of interest statement

Declarations. Conflict of interest: The authors declare no competing interests.

References

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    1. Sujino Y, Kimura F, Tanno J et al (2014) Cardiac magnetic resonance imaging in giant cell myocarditis: intriguing associations with clinical and pathological features. Circulation 129(17):e467–e469. https://doi.org/10.1161/CIRCULATIONAHA.113.005059 - DOI - PubMed
    1. Yang S, Chen X, Li J et al (2021) Late gadolinium enhancement characteristics in giant cell myocarditis. ESC Heart Fail 8(3):2320–2327. https://doi.org/10.1002/ehf2.13276 - DOI - PubMed - PMC

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