Eosinophilic Lung Diseases

Abstract

The diagnosis of eosinophilic lung disease usually relies on characteristic clinical-imaging features and the demonstration of alveolar eosinophilia, while lung biopsy is generally not necessary. The etiology has practical implications, including interruption of a medicinal or illicit drugs, treatment of infections with parasites or fungi, or smoking cessation. The diagnosis of idiopathic eosinophilic pneumonia is considered only once all known causes of eosinophilia have been excluded, especially medications and infections. Treatment of eosinophilic lung diseases involves oral glucocorticoids in most cases and withdrawal of the offending agent when appropriate. Therapies that specifically target the interleukin-5 axis are increasing used.

Keywords: Aspergillus; Eosinophil; Eosinophilic granulomatosis with polyangiitis; Eosinophilic pneumonia; Interstitial lung disease.