Drug Development for Pulmonary Arterial Hypertension: Unleashing the Potential of Single-Patient Studies Using Continuous Monitoring

Martin R Wilkins¹, Sofia S Villar^{2

3}, James Wason⁴, Mark Toshner⁵, Alexander M K Rothman^{6

7}

Affiliations

¹ National Heart and Lung Institute, Imperial College London London UK.
² MRC Biostatistics Unit University of Cambridge Cambridge UK.
³ Papworth Trials Unit Collaboration Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
⁴ Population Health Sciences Institute Newcastle University UK.
⁵ Department of Medicine University of Cambridge Cambridge UK.
⁶ Sheffield Pulmonary Vascular Disease Unit Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust Sheffield UK.
⁷ Department of Clinical Medicine The University of Sheffield Sheffield UK.

Editorial

Martin R Wilkins et al. Pulm Circ. 2025.

. 2025 Oct 15;15(4):e70177.

doi: 10.1002/pul2.70177. eCollection 2025 Oct.

Martin R Wilkins¹, Sofia S Villar^{2

3}, James Wason⁴, Mark Toshner⁵, Alexander M K Rothman^{6

7}

¹ National Heart and Lung Institute, Imperial College London London UK.
² MRC Biostatistics Unit University of Cambridge Cambridge UK.
³ Papworth Trials Unit Collaboration Royal Papworth Hospital NHS Foundation Trust Cambridge UK.
⁴ Population Health Sciences Institute Newcastle University UK.
⁵ Department of Medicine University of Cambridge Cambridge UK.
⁶ Sheffield Pulmonary Vascular Disease Unit Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust Sheffield UK.
⁷ Department of Clinical Medicine The University of Sheffield Sheffield UK.

No abstract available

Figures

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