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Review
. 2025 Oct;60(4):413-421.
doi: 10.1053/j.ro.2025.06.004. Epub 2025 Jul 24.

Cardiothoracic Imaging AI for Cardiac Diseases

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Review

Cardiothoracic Imaging AI for Cardiac Diseases

Satvik Tripathi et al. Semin Roentgenol. 2025 Oct.

Abstract

Artificial intelligence (AI) has transformed medical imaging across disciplines. In cardiothoracic imaging, AI has the potential to impact all modalities, including chest radiography, echocardiography, computed tomography, magnetic resonance imaging, and nuclear cardiology. Use cases include automated structural and functional quantification of anatomic structures, lesion detection and characterization, and novel disease screening opportunities. Here, we discuss techniques and applications specific to cardiovascular diseases, including multimodal AI, coronary artery disease and coronary calcium detection, cardiac structural and functional evaluation, analysis of acute aortic syndromes, and evolving use cases such as pericardial disease evaluation and pulmonary hypertension assessment. We also discuss population health-related aspects of AI, model development challenges, and ethical considerations.

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Conflict of interest statement

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Tessa S. Cook reports a relationship with Bayer that includes: consulting or advisory and speaking and lecture fees. Tessa S Cook reports a relationship with Sectra that includes: consulting or advisory. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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