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Editorial
. 2025 Oct 20.
doi: 10.1038/s41372-025-02444-5. Online ahead of print.

Using a lower platelet transfusion threshold: translating evidence into practice

David A Paul  1   2 , Stephen A Pearlman  3   4 , Ravi M Patel  5
Affiliations
Editorial

Using a lower platelet transfusion threshold: translating evidence into practice

David A Paul et al. J Perinatol. .
No abstract available

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Conflict of interest statement

Competing interests: The authors declare no competing interests.

References

    1. Curley A, Stanworth SJ, Willoughby K, Fustolo-Gunnink SF, Venkatesh V, Hudson C, et al. Randomized trial of platelet-transfusion thresholds in neonates. N Engl J Med. 2019;380:242–51. - DOI - PubMed
    1. Moore CM, D’Amore A, Fustolo-Gunnink S, Hudson C, Newton A, Santamaria BL, et al. Two-year outcomes following a randomised platelet transfusion trial in preterm infants. Arch Dis Child Fetal Neonatal Ed. 2023;108:452–7. - PubMed
    1. Coletti K, Hershey JA, Devine M, Taft J, Schinella J, Ajiboye S et al. An improvement project standardizing low prophylactic platelet transfusion dosing for infants. J Perinatol. 2025. https://doi.org/10.1038/s41372-025-02347-5 .
    1. Lalos N, Brumfiel A, Viehl LT, Pet GC, Lahart A. Development and implementation of restrictive platelet transfusion thresholds in a neonatal intensive care unit. J Perinatol. 2025. https://doi.org/10.1038/s41372-025-02302-4 .
    1. Davenport PE, Chan Yuen J, Briere J, Feldman HA, Sola-Visner MC, Leeman KT. Implementation of a neonatal platelet transfusion guideline to reduce non-indicated transfusions using a quality improvement framework. J Perinatol. 2021;41:1487–94. - DOI - PubMed - PMC

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