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Practice Guideline
. 2025 Oct:215 Suppl 1:110821.
doi: 10.1016/j.resuscitation.2025.110821.

European Resuscitation Council Guidelines 2025 System Saving Lives

Federico Semeraro  1 , Sebastian Schnaubelt  2 , Theresa M Olasveengen  3 , Elena G Bignami  4 , Bernd W Böttiger  5 , Nino Fijačko  6 , Lorenzo Gamberini  7 , Carolina Malta Hansen  8 , Andrew Lockey  9 , Bibiana Metelmann  10 , Camilla Metelmann  11 , Giuseppe Ristagno  12 , Hans van Schuppen  13 , Kaushila Thilakasiri  14 , Koenraad G Monsieurs  15 ; ERC Systems Saving Lives Collaborator Group
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Practice Guideline

European Resuscitation Council Guidelines 2025 System Saving Lives

Federico Semeraro et al. Resuscitation. 2025 Oct.

Abstract

The European Resuscitation Council (ERC) developed the Systems Saving Lives Guidelines, based on the 2025 ILCOR Consensus on Science with Treatment Recommendations (CoSTR). These Guidelines addresses various topics including the Chain of Survival, advocacy, CPR awareness campaigns, Kids Save Lives, resuscitation in low-resource settings, social media, first responders, EMS organisation for cardiac arrest, in-hospital cardiac arrest management, cardiac arrest centres, system performance improvement, survivors and co-survivors, and new technologies and artificial intelligence.

Keywords: Advocacy; Artificial intelligence; Awareness campaign; Cardiac arrest; Cardiac arrest centres; Co-survivors; Emergency medical service; First responders; In-hospital cardiac arrest; Kids save lives; Low resource settings; Social media; Survivors; Systems saving lives; World restart a heart.

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Conflict of interest statement

Declaration of competing interest Declarations of competing interests for all ERC Guidelines authors are displayed in a COI table which can be found online at https://doi.org/10.1016/j.resuscitation.2025.110821.

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