Differential Odds of COVID-19 Infection Associated with Household and Workplace Exposures in U.S. Health Care Personnel
- PMID: 41118238
- DOI: 10.1097/JOM.0000000000003586
Differential Odds of COVID-19 Infection Associated with Household and Workplace Exposures in U.S. Health Care Personnel
Abstract
Objective: To evaluate associations between occupational and non-occupational COVID-19 exposures, household characteristics, and COVID-19 infection risk among health care personnel (HCP).
Methods: Nested analysis of HCP enrolled in a multisite vaccine effectiveness study. COVID-19 infection was confirmed through source documentation. Exposures and household characteristics were self-reported.
Results: HCP with household COVID-19 exposure had significantly higher infection odds, while workplace exposure was associated with decreased odds of infection. No associations were observed for community exposures, living with children, or living with unvaccinated household members.
Conclusion: Household exposure posed greater COVID-19 risk to HCP unlike exposures in the workplace. Combined with demonstrated vaccine effectiveness, these findings suggest that workplace infection control measures were successful, while interventions targeting household transmission may be critical for protecting HCP.
Keywords: COVID-19; Health Personnel; SARS-CoV-2.
Copyright © 2025 Written work prepared by employees of the Federal Government as part of their official duties is, under the U.S. Copyright Act, a “work of the United States Government” for which copyright protection under Title 17 of the United States Code is not available. As such, copyright does not extend to the contributions of employees of the Federal Government.
Conflict of interest statement
Conflicts of Interests: None declared.
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