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Review
. 2025 Nov;109(6):1331-1344.
doi: 10.1016/j.mcna.2025.04.011. Epub 2025 Jun 9.

Addressing Comorbidities in Heart Failure

Affiliations
Review

Addressing Comorbidities in Heart Failure

Rachel Tobin et al. Med Clin North Am. 2025 Nov.

Abstract

Heart failure (HF) comorbidities are extremely common and complicate management due to increased prescriptions and adverse drug effects, declining functional status, and more frequent health care utilization. Comorbidities are associated with poor outcomes in these patients, with worsened mortality, hospitalization, and quality of life. Clinicians should understand how to address common HF comorbidities to provide optimal care of patients with HF and avoid adverse outcomes.

Keywords: Anemia; Atrial fibrillation; Chronic kidney disease; Comorbidities; Diabetes; Heart failure; Hypertension; Management.

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Conflict of interest statement

Disclosures None.