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. 2025 Oct;73(10):3269-3272.
doi: 10.1111/jgs.19615. Epub 2025 Jul 5.

Emergency Department Visits for Bleeding by Adults Aged ≥ 80 Years Receiving Direct-Acting Oral Anticoagulants

Andrew I Geller  1 , Nadine Shehab  1   2 , Maribeth C Lovegrove  1 , Nina J Weidle  1   3 , Nimalie D Stone  1 , Pieter A Cohen  1   4
Affiliations

Emergency Department Visits for Bleeding by Adults Aged ≥ 80 Years Receiving Direct-Acting Oral Anticoagulants

Andrew I Geller et al. J Am Geriatr Soc. 2025 Oct.
No abstract available

Keywords: Oral anticoagulants; adverse drug events; anticoagulant‐related bleeding; direct‐acting oral anticoagulants; emergency department visits.

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Conflict of interest statement

Dr. Cohen reported receiving grants from Consumers Union and The Pew Charitable Trusts and personal fees from UpToDate outside the submitted work. No other disclosures were reported.

References

    1. Ko D, Lin KJ, Bessette LG, et al. Trends in Use of Oral Anticoagulants in Older Adults With Newly Diagnosed Atrial Fibrillation, 2010-2020. JAMA Netw Open. 2022;5(11):e2242964. 10.1001/jamanetworkopen.2022.42964 - DOI - PMC - PubMed
    1. Budnitz DS, Shehab N, Lovegrove MC, Geller AI, Lind JN, Pollock DA. US Emergency Department Visits Attributed to Medication Harms, 2017-2019. JAMA. 2021;326(13):1299–1309. 10.1001/jama.2021.13844 - DOI - PMC - PubMed
    1. Geller AI, Shehab N, Lovegrove MC, Weidle NJ, Budnitz DS. Bleeding related to oral anticoagulants: Trends in US emergency department visits, 2016-2020. Thromb Res. 2023;225:110–115. 10.1016/j.thromres.2023.03.010 - DOI - PMC - PubMed
    1. Shehab N, Sperling LS, Kegler SR, Budnitz DS. National estimates of emergency department visits for hemorrhage-related adverse events from clopidogrel plus aspirin and from warfarin. Arch Intern Med. 2010;170(21):1926–1933. 10.1001/archinternmed.2010.407 - DOI - PubMed

    1. 45 C.F.R. part 46; 21 C.F.R. part 56; 42 U.S.C. §241(d); 5 U.S.C. §552a; 44 U.S.C. §3501 et seq.

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