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Review
. 2025 Oct 27;26(1):68.
doi: 10.1007/s11934-025-01300-5.

Management of Stone Disease in the Spina Bifida Patient

Meghan F Davis  1 , Kyle L Yu  2 , Arun K Srinivasan  3
Affiliations
Review

Management of Stone Disease in the Spina Bifida Patient

Meghan F Davis et al. Curr Urol Rep. .

Abstract

Purpose of the review: This review provides a detailed overview of the specifics of presentation, diagnosis, and management of upper and lower urinary tract stone disease for individuals with spina bifida.

Recent findings: Recent studies highlight the significant burden of stone disease for spina bifida patients. Individuals with spina bifida require lifelong urologic care. They are more likely to have stone disease and have complications from management. This is a particularly salient issue for patients who have undergone bladder augmentation. Given the frequency and severity of these issues, it is critical that urologists be familiar with the nuances of stone disease in this population. Further strategies are needed to decrease the morbidity associated with stone disease amongst individuals with spina bifida.

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Conflict of interest statement

Declarations. Human/Animal Studies Informed Consent Statement: This article does not contain any studies with human or animal subjects performed by any of the authors. Ethical Considerations & Disclosure(s): Exempt, not human subjects research per IRB. Competing Interests: The authors declare no competing interests.

References

    1. Szymanski KM, et al. Additional surgeries after bladder augmentation in patients with spina bifida in the 21st century. J Urol. 2020;203(6):1207–13. - PubMed
    1. Ramachandra P, et al. Children with spinal abnormalities have an increased health burden from upper tract urolithiasis. Urology. 2014;83(6):1378–82. - PubMed
    1. VanderVeer-Harris N et al. Comorbid Urolithiasis Significantly Increases Utilization Across Healthcare Settings for Individuals With Spina Bifida. Urology, 2025. - PubMed
    1. Wang HH, et al. Complications of surgical management of upper tract calculi in spina bifida patients: analysis of nationwide data. J Urol. 2015;193(4):1270–4. - PMC - PubMed
    1. Salama AK, et al. Incidence of nephrolithiasis after bladder augmentation in people with spina bifida. J Pediatr Urol. 2021;17(4):e5211–7. - PubMed

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