In Reply: Letter: Predicting Intracranial Pressure Levels: A Deep Learning Approach Using Computed Tomography Brain Scans

Dimitrios Theodoropoulos¹, Eleftherios Trivizakis², Kostas Marias^{2

3}, Nektaria Xirouchaki⁴, Antonios Vakis¹, Efrosini Papadaki^{1

5}, Apostolos Karantanas^{1

5}, Dimitrios A Karabetsos⁶

Affiliations

¹ School of Medicine, University of Crete, Heraklion, Greece.
² Computational Biomedicine Laboratory, FORTH-ICS, Heraklion, Greece.
³ Department of Electrical and Computer Engineering, Hellenic Mediterranean University, Heraklion, Greece.
⁴ Intensive Care Unit, Heraklion University Hospital, Heraklion, Greece.
⁵ Department of Radiology, Heraklion University Hospital, Heraklion, Greece.
⁶ Department of Neurosurgery, Heraklion University Hospital, Heraklion, Greece.

Dimitrios Theodoropoulos et al. Neurosurgery. 2025.

. 2025 Oct 27.

doi: 10.1227/neu.0000000000003831. Online ahead of print.

Dimitrios Theodoropoulos¹, Eleftherios Trivizakis², Kostas Marias^{2

3}, Nektaria Xirouchaki⁴, Antonios Vakis¹, Efrosini Papadaki^{1

5}, Apostolos Karantanas^{1

5}, Dimitrios A Karabetsos⁶

¹ School of Medicine, University of Crete, Heraklion, Greece.
² Computational Biomedicine Laboratory, FORTH-ICS, Heraklion, Greece.
³ Department of Electrical and Computer Engineering, Hellenic Mediterranean University, Heraklion, Greece.
⁴ Intensive Care Unit, Heraklion University Hospital, Heraklion, Greece.
⁵ Department of Radiology, Heraklion University Hospital, Heraklion, Greece.
⁶ Department of Neurosurgery, Heraklion University Hospital, Heraklion, Greece.

No abstract available

References

1. de Oliveira Manduca Palmiero H, Gadelha Figueiredo E. Letter: Predicting intracranial pressure levels: a deep learning approach using computed tomography brain scans. Neurosurgery. 2025;XX(X):XXX-XXX.
1. Theodoropoulos D, Trivizakis E, Marias K, et al. Predicting intracranial pressure levels: a deep learning approach using computed tomography brain scans. Neurosurgery. 2025;XX(X):XXX-XXX.
1. Carney N, Totten AM, O’Reilly C, et al. Guidelines for the management of severe traumatic brain injury, fourth edition. Neurosurgery. 2017;80(1):6-15.
1. Helbok R, Olson DM, Le Roux P, et al. Intracranial pressure and cerebral perfusion pressure monitoring in non-TBI patients: special considerations. Neurocrit Care. 2014;21(Suppl 2):S85-S94.
1. Wagner MW, Namdar K, Biswas A, Monah S, Khalvati F, Ertl-Wagner BB. Radiomics, machine learning, and artificial intelligence—what the neuroradiologist needs to know. Neuroradiology. 2021;63(12):1957-1967.