Vascular clearance of venezuelan equine encephalomyelitis viruses as a correlate to virulence for rhesus monkeys
- PMID: 411457
- DOI: 10.1007/BF01314490
Vascular clearance of venezuelan equine encephalomyelitis viruses as a correlate to virulence for rhesus monkeys
Abstract
The epizootic Trinidad donkey strain of Venezuelan equime encephalomyelitis virus (VEE) was cleared slowly from the circulation of rhesus monkeys following intravenous inoculation, while the live, attenuated vaccine strain, TC-83, was cleared rapidly. The efficent clearance of TC-83 vaccine may be a factor in the lower viremia and benign course of TC-83 virus infection in rhesus monkeys.