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. 1972 Sep 1;136(3):650-5.
doi: 10.1084/jem.136.3.650.

Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays

P Wernet, T Feizi, H G Kunkel

Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays

P Wernet et al. J Exp Med. .

Abstract

The complement-mediated cytotoxicity assay has been used to demonstrate surface immunoglobulin determinants on human peripheral blood lymphocytes. In two individuals with monoclonal serum IgM components, idiotypic antisera demonstrated similar components on a significant proportion of the peripheral blood lymphocytes.

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