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. 1972 Sep;69(9):2483-7.
doi: 10.1073/pnas.69.9.2483.

Molecular mechanism for genetic recombination

Molecular mechanism for genetic recombination

H M Sobell. Proc Natl Acad Sci U S A. 1972 Sep.

Abstract

Symmetry considerations of proteinnucleic acid interaction suggest the existence of an alternate branched configuration for DNA induced by binding specific structural proteins to symmetrically arranged polynucleotide base sequences. The concept that such sequences exist at the ends of genes or operons leads to a molecular model for genetic recombination in eukaryotic cells.

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