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. 1972 Sep;69(9):2492-4.
doi: 10.1073/pnas.69.9.2492.

Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen

S von Kleist, G Chavanel, P Burtin

Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen

S von Kleist et al. Proc Natl Acad Sci U S A. 1972 Sep.

Abstract

A glycoprotein present in normal human tissue is characterized that is neither organ- nor tumor-specific (nonspecific crossreacting antigen) and that crossreacts (by the Ouchterlony double-diffusion technique) with the carcinoembryonic antigen. This immunological relationship indicates common determinants on the molecules of both antigens. We demonstrate that the nonspecific crossreacting antigen is not a fragment of the carcinoembryonic antigen molecule.

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References

    1. Cancer Res. 1969 Nov;29(11):1961-4 - PubMed
    1. Proc Natl Acad Sci U S A. 1969 Sep;64(1):161-7 - PubMed
    1. Int J Cancer. 1970 Nov 15;6(3):352-60 - PubMed
    1. N Engl J Med. 1971 Jul 15;285(3):138-41 - PubMed
    1. N Engl J Med. 1972 Jan 13;286(2):83-6 - PubMed

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