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. 2025;32(5):532-533.
doi: 10.5603/cj.103861.

Ventricular arrhythmia aggravated by pregnancy

Agnieszka Katarzyńska-Szymańska  1 , Filip Waśniewski  2 , Lidia Chmielewska-Michalak  1 , Olga Trojnarska  1 , Przemysław Mitkowski  1
Affiliations

Ventricular arrhythmia aggravated by pregnancy

Agnieszka Katarzyńska-Szymańska et al. Cardiol J. 2025.
No abstract available

Keywords: arrhythmia; arrhythmias in pregnancy; pregnancy.

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Conflict of interest statement

Conflict of interest: P.M. is receiving speaking fees from Holsten Pharma.

Figures

Figure 1
Figure 1
A, B. ECGs (25 mm/sec, 10 mm/mV): (A) on admission — ventricular bigeminy, (B) under F+MT therapy — normal sinus rhythm with a heart rate of 78 bpm; C. A comparison of 24-hour ECG Holter parameters on admission and under F+MT treatment. Values in brackets show the percentage of all beats recorded throughout the day that the VEs amount to. A significant reduction in VA burden can be observed, the number of VEs has been reduced by about a half, while VTs have completely ceased; D. A graph comparing the hourly breakdown of VEs on admission (blue) and under F+MT treatment (orange). Throughout most hours the number of VEs has decreased after the initiation of the treatment. A sinusoid distribution of VEs while under F+MT therapy can be observed, it may be related to the pharmacokinetics of flecainide and metoprolol tartrate — they were administered at 7 a.m. and 6 p.m., while their peak plasma levels occur 1–6 and 3–4 h after intake, respectively; E. A comparison of chosen parameters measured in TTEs performed during the first hospitalization before and after the initiation of F+MT therapy and during the check-up before termination of pregnancy 6 weeks later. A generalized improvement in TTE images can be observed following the initiation of the antiarrhythmic treatment: the heart chambers have decreased in size, LVEF has improved, while MR and TR have diminished; ECG — electrocardiogram; F+MT — flecainide with metoprolol tartrate; LA — left atrium; LV — left ventricle; LVEF — left ventricular ejection fraction; MR — mitral regurgitation; TR — tricuspid regurgitation; TTE — transthoracic echocardiography; VA — ventricular arrhythmia; VEs — ventricular extrasystoles; VTs — ventricular tachycardias
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