Genetics of cycloheximide resistance in Tetrahymena
- PMID: 411713
- PMCID: PMC1213740
- DOI: 10.1093/genetics/87.2.275
Genetics of cycloheximide resistance in Tetrahymena
Abstract
Cycloheximide resistance in Tetrahymena is inducible by mutagenesis. Two mutations, isolated independently from genetically different strains, were analyzed. The two mutations, Chx-1 and Chx-2, were found to be alleles at the same locus. A specific analysis is presented which may serve as a model for strategies employing an independent manipulation of the micro-and macronuclei of this organism for genetic studies.
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