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Clinical Trial
. 1972 Dec 16;4(5841):635-8.
doi: 10.1136/bmj.4.5841.635.

Early clinical experience with bleomycin in the United Kingdom in series of 105 patients

K E Halnan, N M Bleehen, T B Brewin, T J Deeley, D F Harrison, C Howland, P B Kunkler, G L Ritchie, E Wiltshaw, I D Todd
Clinical Trial

Early clinical experience with bleomycin in the United Kingdom in series of 105 patients

K E Halnan et al. Br Med J. .

Abstract

The results of treating a series of 105 patients (79 with advanced squamous cell carcinoma, 21 with advanced lymphoma, and 5 with miscellaneous tumours) with bleomycin are described. The drug was usually given as a single agent. Four patients with squamous cell carcinoma showed complete regression and there was partial regression in 25. Side effects were frequent, particularly skin changes and stomatitis; death from pneumonitis occurred in one patient.

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