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Case Reports
. 2025 Jul-Sep;69(3):455-459.
doi: 10.22336/rjo.2025.71.

Surgical Management of Complicated Chronic Uveitis: A Case Report

Andreea Alexandra Mihaela Muşat  1   2 , Nicoleta Zamfiroiu-Avidis  2 , Cornel Ştefan  3 , Andreea Schmitzer  1   2 , Gabriela Muşat  1 , Gabriela Udrea  4 , Ioana Stella Popescu  3 , Ovidiu Muşat  1   3
Affiliations
Case Reports

Surgical Management of Complicated Chronic Uveitis: A Case Report

Andreea Alexandra Mihaela Muşat et al. Rom J Ophthalmol. 2025 Jul-Sep.

Abstract

Background: Chronic uveitis is a common vision-threatening condition that can lead to many complications and may not respond to conventional medical therapy. This case report aims to emphasize the need for a personalized approach to these challenging cases to reestablish visual function.

Case presentation: A 29-year-old female patient, C.F., developed bilateral anterior uveitis of unknown origin that evolved into a chronic, refractory form. Topical, as well as systemic therapy, failed to control the inflammation, leading to complications in the form of cataract and secondary glaucoma. Surgical management involved Ahmed valve implantation in both eyes and pars plana vitrectomy.

Discussion: This particularly challenging case highlights the complex challenges in managing uveitis of unknown etiology, especially when complicated by secondary glaucoma. In young patients, progressive structural changes due to inflammation can rapidly lead to permanent vision loss. A combination of surgical procedures resulted in favorable anatomical and functional outcomes; however, long-term follow-ups remain essential to monitor for recurrent inflammation, intraocular pressure fluctuations, and other potential complications.

Conclusion: This case highlights the challenges and the need for a multidisciplinary approach in chronic, treatment-resistant uveitis with secondary complications.

Keywords: chronic uveitis; complicated cataract; uveitic glaucoma; vitrectomy.

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Conflict of interest statement

The authors state no conflict of interest.

Figures

Fig. 1
Fig. 1
A, B Humphrey visual field test in OD (right) showing total scotoma and Goldmann visual field test in OS (left) showing a dense central scotoma and a constricted field, suggesting advanced glaucoma
Fig. 2
Fig. 2
A, B Anterior segment of OD (right) and OS (left) showing patent peripheral iridotomies, Ahmed Valves, IOLs in posterior chambers, and no signs of inflammation
Fig. 3
Fig. 3
A, B Goldmann visual field tests in OD (right) and OS (left) indicate severe peripheral field loss
See this image and copyright information in PMC

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