The PTPN22 R620W polymorphism is associated with inclusion body myositis - data from the UKMyoNet study

Yuhui Li^{1

2

3}, Gang Chen², Neil J McHugh⁴, Sarah L Tansley^{4

5}, James B Lilleker^{3

6}, Choon-Guan Chua⁷, Janine A Lamb², Hector Chinoy^{3

8

9}; UKMyoNet contributors

Collaborators, Affiliations

UKMyoNet contributors:
Yasmeen Ahmed, Raymond Armstrong, Robert Bernstein, Carol Black, Simon Bowman, Ian Bruce, Robin Butler, John Carty, Chandra Chattopadhyay, Easwaradhas Chelliah, Fiona Clarke, Peter Dawes, Joseph Devlin, Christopher Edwards, Paul Emery, John Fordham, Alexander Fraser, Hill Gaston, Patrick Gordon, Bridget Griffiths, Harsha Gunawardena, Frances Hall, Beverley Harrison, Elaine Hay, Lesley Horden, John Isaacs, Adrian Jones, Sanjeet Kamath, Thomas Kennedy, George Kitas, Peter Klimiuk, Sally Knights, John Lambert, Peter Lanyon, Ramasharan Laxminarayan, Bryan Lecky, Raashid Luqmani, Jeffrey Marks, Michael Martin, Dennis McGonagle, Neil McHugh, Frank McKenna, John McLaren, Michael McMahon, Euan McRorie, Peter Merry, Sarah Miles, James Miller, Anne Nicholls, Jennifer Nixon, Voon Ong, John Packham, Nicolo Pipitone, Michael Plant, Gillian Pountain, Thomas Pullar, Mark Roberts, Paul Sanders, David Scott, David Scott, Michael Shadforth, Thomas Sheeran, Arul Srinivasan, David Swinson, Lee-Suan Teh, Michael Webley, Brian Williams, Jonathan Winer

¹ Department of Rheumatology and Immunology and Beijing Key Laboratory for Rheumatism and Immune Diagnosis, Peking University People's Hospital, Beijing, China.
² Epidemiology and Public Health Group, School of Health Sciences, The University of Manchester, Manchester, UK.
³ Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
⁴ Department of Life Sciences, University of Bath, Bath, UK.
⁵ Royal National Hospital for Rheumatic Diseases, Royal United Hospitals NHS Foundation Trust, Bath, UK.
⁶ Manchester Centre for Clinical Neurosciences, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, UK.
⁷ Tan Tock Seng Hospital, NHG Health, Singapore.
⁸ NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
⁹ Department of Rheumatology, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, UK.

Yuhui Li et al. Rheumatology (Oxford). 2025.

. 2025 Nov 4:keaf592.

doi: 10.1093/rheumatology/keaf592. Online ahead of print.

Yuhui Li^{1

2

3}, Gang Chen², Neil J McHugh⁴, Sarah L Tansley^{4

5}, James B Lilleker^{3

6}, Choon-Guan Chua⁷, Janine A Lamb², Hector Chinoy^{3

8

9}; UKMyoNet contributors

UKMyoNet contributors:
Yasmeen Ahmed, Raymond Armstrong, Robert Bernstein, Carol Black, Simon Bowman, Ian Bruce, Robin Butler, John Carty, Chandra Chattopadhyay, Easwaradhas Chelliah, Fiona Clarke, Peter Dawes, Joseph Devlin, Christopher Edwards, Paul Emery, John Fordham, Alexander Fraser, Hill Gaston, Patrick Gordon, Bridget Griffiths, Harsha Gunawardena, Frances Hall, Beverley Harrison, Elaine Hay, Lesley Horden, John Isaacs, Adrian Jones, Sanjeet Kamath, Thomas Kennedy, George Kitas, Peter Klimiuk, Sally Knights, John Lambert, Peter Lanyon, Ramasharan Laxminarayan, Bryan Lecky, Raashid Luqmani, Jeffrey Marks, Michael Martin, Dennis McGonagle, Neil McHugh, Frank McKenna, John McLaren, Michael McMahon, Euan McRorie, Peter Merry, Sarah Miles, James Miller, Anne Nicholls, Jennifer Nixon, Voon Ong, John Packham, Nicolo Pipitone, Michael Plant, Gillian Pountain, Thomas Pullar, Mark Roberts, Paul Sanders, David Scott, David Scott, Michael Shadforth, Thomas Sheeran, Arul Srinivasan, David Swinson, Lee-Suan Teh, Michael Webley, Brian Williams, Jonathan Winer

¹ Department of Rheumatology and Immunology and Beijing Key Laboratory for Rheumatism and Immune Diagnosis, Peking University People's Hospital, Beijing, China.
² Epidemiology and Public Health Group, School of Health Sciences, The University of Manchester, Manchester, UK.
³ Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
⁴ Department of Life Sciences, University of Bath, Bath, UK.
⁵ Royal National Hospital for Rheumatic Diseases, Royal United Hospitals NHS Foundation Trust, Bath, UK.
⁶ Manchester Centre for Clinical Neurosciences, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, UK.
⁷ Tan Tock Seng Hospital, NHG Health, Singapore.
⁸ NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
⁹ Department of Rheumatology, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, Salford, UK.

No abstract available

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