Myelination inhibition factor: dissociation from induction of experimental allergic encephalomyelitis
- PMID: 4119452
- DOI: 10.1126/science.179.4074.689
Myelination inhibition factor: dissociation from induction of experimental allergic encephalomyelitis
Abstract
Sensitization of guinea pigs with purified myelin basic protein induces experimental allergic encephalomyelitis (EAE) but does not induce a serum factor which inhibits myelin formation in vitro. This factor, induced by some unidentified constituent of whole central nervous system tissue, should not be characterized as a component of "EAE serum."
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