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. 1973 Feb 16;179(4074):689-90.
doi: 10.1126/science.179.4074.689.

Myelination inhibition factor: dissociation from induction of experimental allergic encephalomyelitis

M W Kies, B F Driscoll, F J Seil, E C Alvord Jr

Myelination inhibition factor: dissociation from induction of experimental allergic encephalomyelitis

M W Kies et al. Science. .

Abstract

Sensitization of guinea pigs with purified myelin basic protein induces experimental allergic encephalomyelitis (EAE) but does not induce a serum factor which inhibits myelin formation in vitro. This factor, induced by some unidentified constituent of whole central nervous system tissue, should not be characterized as a component of "EAE serum."

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