A simulation study of the impact of population-wide lifestyle modifications on life expectancy in the Chinese population
- PMID: 41203624
- PMCID: PMC12594753
- DOI: 10.1038/s41467-025-64824-x
A simulation study of the impact of population-wide lifestyle modifications on life expectancy in the Chinese population
Abstract
It is uncertain how much life expectancy of the Chinese population would improve under current and greater policy targets on lifestyle-based risk factors for chronic diseases and mortality. Here we report a simulation of how improvements in four risk factors, namely smoking, alcohol use, physical activity and diet, could affect mortality. We show that in the ideal scenario, that is, all people who currently smoke quit smoking, excessive alcohol use was reduced to moderate intake, people under 65 increased moderate physical activity by one hour and those aged 65 and older increased by half an hour per day, and all participants ate 200 g more fresh fruits and 50 g more fish/seafood per day, life expectancy at age 30 would increase by 4.83 and 5.39 years for men and women, respectively. In a more moderate risk reduction scenario referred to as the practical scenario, where improvements in each lifestyle factor were approximately halved, the gains in life expectancy at age 30 could be half those of the ideal scenario. However, the possibility to realize these estimates in practise may be influenced by population-wide adherence to lifestyle recommendations.
© 2025. The Author(s).
Conflict of interest statement
Competing interests: The authors declare no competing interests.
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References
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- Zhang, Y. B. et al. Combined lifestyle factors, all-cause mortality and cardiovascular disease: a systematic review and meta-analysis of prospective cohort studies. J. Epidemiol. Community Health75, 92–99 (2021). - PubMed
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- Jin, G. et al. Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study. Lancet Oncol.21, 1378–1386 (2020). - PubMed
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- 82192900/National Natural Science Foundation of China (National Science Foundation of China)
- 81390540/National Natural Science Foundation of China (National Science Foundation of China)
- 91846303/National Natural Science Foundation of China (National Science Foundation of China)
- 81941018/National Natural Science Foundation of China (National Science Foundation of China)
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