[Spontaneous regression of pulmonary metastases from hypernephroma: report of a case and review of literature (author's transl)]

Abstract

Until now there are reported some 60 cases of spontaneous regression of pulmonary metastases from hypernephroma. An own case is shown up: There was taken nephrectomy and following local radiation of hypernephroma in a 59 years old male patient in spite of pulmonary metastases. 8 months after operation these metastases had disappeared. There was no indication for any metastases in radiologic and scintigrafic examination even 4 years following up neither in lungs nor in other organ. The causality of hormones and autoantibodies - perphaps additionally stimulated by wound infection-in the phenomenon of spontaneous regression of pulmonary hypernephroma-metastases is discussed. According to the literature and to experience in an own case nephrectomy and following local radiation - possibly additional progesterone-therapy for one year - is recommended in hypernephroma even in case of pulmonary metastases.