Postoperative Transfusion in Patients at High Cardiac Risk: Evidence, Uncertainty, and Nuance

Affiliations

¹ Division of Transfusion Medicine, Department of Pathology, Microbiology & Immunology, Vanderbilt University, Nashville, Tennessee.
² Division of Transfusion Medicine, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Comment

Jeremy W Jacobs et al. JAMA. 2025.

. 2025 Dec 23;334(24):2171-2173.

doi: 10.1001/jama.2025.21559.

¹ Division of Transfusion Medicine, Department of Pathology, Microbiology & Immunology, Vanderbilt University, Nashville, Tennessee.
² Division of Transfusion Medicine, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

No abstract available

Comment on

Liberal or Restrictive Postoperative Transfusion in Patients at High Cardiac Risk: The TOP Randomized Clinical Trial.
Kougias P, Sharath SE, Zhan M, Carson JL, Norman LE, Mi Z, Pal R, Dosluoglu H, Modrall JG, Sarosi GA Jr, Nelson P, Arya S, Scrymgeour A, Ollison J, Calais LA, Nambi V, Gregg LP, Abdullah SM, Tsai S, Becker N, Choi JC, Chiu L, Scali S, Barshes NR, Awad S, Moursi M, Koopmann MC, Sally M, Ihnat D, Ramaswamy A, Gasper W, Tzeng E, Wilson MA, Tang G, Huang G, Biswas K; TOP Trial Investigators. Kougias P, et al. JAMA. 2025 Dec 23;334(24):2197-2207. doi: 10.1001/jama.2025.20841. JAMA. 2025. PMID: 41205227 Clinical Trial.