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Review
. 2026 Jan;110(1):31-44.
doi: 10.1016/j.mcna.2025.05.008. Epub 2025 Jul 4.

Rhinosinusitis

Oliver Liu-Lam  1 , Kathryn M Hardin  1 , Zachary A Warren  1 , Thomas S Edwards  2
Affiliations
Review

Rhinosinusitis

Oliver Liu-Lam et al. Med Clin North Am. 2026 Jan.

Abstract

Rhinosinusitis is a significant contributor to patient morbidity, impacting quality of life and health care costs. This article provides an evidence-based review of rhinosinusitis, including classification, pathophysiology, diagnostic criteria, and management strategies. Special emphasis is placed on differentiating rhinosinusitis from other conditions, differences between acute and chronic sinusitis, the role of imaging, and indications for referral for potential surgical intervention.

Keywords: Acute rhinosinusitis; Allergic rhinitis; Chronic sinusitis; Rhinosinusitis; Sinus infection; Sinusitis.

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Conflict of interest statement

Disclosure O. Liu-Lam, K.M. Hardin, Z.A. Warren: Nothing to disclose. T.S. Edwards: Scientific advisory board member and research support from Sanofi-Aventis U.S., LLC, United States, and Regeneron Pharmaceuticals Inc., United States, for biologic therapies in CRSwNP.

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