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. 1973 Apr 15;180(4082):203-5.
doi: 10.1126/science.180.4082.203.

Hepatitis B virus antigen: validation and immunologic characterization of low-titer serums with 125 I-antibody

C M Ling, H Irace, R Decker, L R Overby

Hepatitis B virus antigen: validation and immunologic characterization of low-titer serums with 125 I-antibody

C M Ling et al. Science. .

Abstract

Radioimmunnoassay was used to determine the serologic subspecificities of 85 blood donor serums positive for hepatitis B virus-associated antigen. There was complete agreement with results obtained by immunoprecipitatiotn of 43 serums. The remaining 42 serums were negative by immunoprecipitation but followed type-specific immunology by radioimmunoassay, and this served as a validation for authentic hepatitis B virus antigen.

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