Margins matter: raising the bar for thermal ablation through quantitative imaging validation in COVER-ALL
- PMID: 41216284
- PMCID: PMC12596454
- DOI: 10.21037/tgh-25-83
Margins matter: raising the bar for thermal ablation through quantitative imaging validation in COVER-ALL
Keywords: Ablation techniques; ablative margins; image registration; liver neoplasms; quantitative imaging biomarkers.
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://tgh.amegroups.com/article/view/10.21037/tgh-25-83/coif). E.W.J. reports honorarium from Varian to speak at the British Society of Interventional Radiology, 2024, and honorarium from Philips to attend a round table discussion regarding CT hepatic angiography. R.B. received funding for scientific studies from Siemens Healthineers (Erlangen, Germany). The authors have no other conflicts of interest to declare.
Comment on
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Software-based versus visual assessment of the minimal ablative margin in patients with liver tumours undergoing percutaneous thermal ablation (COVER-ALL): a randomised phase 2 trial.Lancet Gastroenterol Hepatol. 2025 May;10(5):442-451. doi: 10.1016/S2468-1253(25)00024-X. Epub 2025 Mar 13. Lancet Gastroenterol Hepatol. 2025. PMID: 40090348 Clinical Trial.
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