OBEClust: joining forces to prevent obesity

Manuel Tena-Sempere^{1

2

3}, Dimitrios-Dionyssios Koutsouris⁴, George Dedoussis⁵, Jeroen Lakerveld⁶, Karl-Heinz Wagner^{7

8}, Itziar Tueros⁹, Philippe Froguel^{10

11}, Torsten Bohn¹², Paulo J Oliveira^{13

14}

Affiliations

¹ Department of Cell Biology, Physiology and Immunology, University of Córdoba, Córdoba, Spain. fi1tesem@uco.es.
² Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain. fi1tesem@uco.es.
³ CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Córdoba, Spain. fi1tesem@uco.es.
⁴ Biomedical Engineering Laboratory, Institute of Communication and Computer Systems (ICCS), Athens, Greece.
⁵ Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens, Greece.
⁶ Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
⁷ Department of Nutritional Sciences, University of Vienna, Vienna, Austria.
⁸ Research Platform Active Aging, University of Vienna, Vienna, Austria.
⁹ AZTI, Food Research, Basque Research and Technology Alliance (BRTA), Derio, Spain.
¹⁰ Université de Lille, Inserm UMR1283, CNRS UMR8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University Hospital, Lille, France.
¹¹ Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
¹² Nutrition and Health Research Group, Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.
¹³ CNC-UC, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
¹⁴ CIBB, Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal.

PMID: 41219440
DOI: 10.1038/s41574-025-01212-x

OBEClust: joining forces to prevent obesity

Manuel Tena-Sempere et al. Nat Rev Endocrinol. 2025.

. 2025 Nov 11.

doi: 10.1038/s41574-025-01212-x. Online ahead of print.

Authors

Affiliations

¹ Department of Cell Biology, Physiology and Immunology, University of Córdoba, Córdoba, Spain. fi1tesem@uco.es.
² Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain. fi1tesem@uco.es.
³ CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Córdoba, Spain. fi1tesem@uco.es.
⁴ Biomedical Engineering Laboratory, Institute of Communication and Computer Systems (ICCS), Athens, Greece.
⁵ Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens, Greece.
⁶ Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
⁷ Department of Nutritional Sciences, University of Vienna, Vienna, Austria.
⁸ Research Platform Active Aging, University of Vienna, Vienna, Austria.
⁹ AZTI, Food Research, Basque Research and Technology Alliance (BRTA), Derio, Spain.
¹⁰ Université de Lille, Inserm UMR1283, CNRS UMR8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University Hospital, Lille, France.
¹¹ Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
¹² Nutrition and Health Research Group, Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.
¹³ CNC-UC, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
¹⁴ CIBB, Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal.

PMID: 41219440
DOI: 10.1038/s41574-025-01212-x

No abstract available

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Conflict of interest statement

Competing interests: The authors declare no competing interests.

References

1. World Health Organization. WHO European Regional Obesity Report 2022. WHO https://www.who.int/europe/publications/i/item/9789289057738 (2022).
1. GBD 2021 Adult BMI Collaborators. Global, regional, and national prevalence of adult overweight and obesity, 1990-2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021. Lancet 405, 813–838 (2025). - DOI
1. Hildebrand, S. & Pfeifer, A. The obesity pandemic and its impact on non-communicable disease burden. Pflugers Arch. 477, 657–668 (2025). - DOI - PubMed - PMC
1. Xie, F. et al. Global, regional, and national burden of mortality and DALYs attributable to high body mass index from 1990 to 2021 with projections to 2036. BMC Public Health 25, 2053 (2025). - DOI - PubMed - PMC
1. Sweis, N. J. The economic burden of obesity in 2024: a cost analysis using the value of a statistical life. Critical Public Health 34, 1–13 (2024). - DOI

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OBEClust: joining forces to prevent obesity

Affiliations

OBEClust: joining forces to prevent obesity

Authors

Affiliations

Conflict of interest statement

References

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