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Review
. 2025 Dec;43(4):707-738.
doi: 10.1016/j.anclin.2025.07.009. Epub 2025 Sep 6.

Regional Anesthesia and Analgesia for Acute Trauma Patients

Ron E Samet  1 , Elisabeth B Powelson  2 , Christopher R Parrino  3 , Ian R Slade  4
Affiliations
Review

Regional Anesthesia and Analgesia for Acute Trauma Patients

Ron E Samet et al. Anesthesiol Clin. 2025 Dec.

Abstract

Regional anesthesia in acute trauma care is gaining popularity due to its benefits, advancements in techniques and equipment, and improved training. Nerve blocks are increasingly performed in trauma settings by various health care providers, including anesthesiologists, emergency medicine and acute care practitioners, and even prehospital providers. Emerging studies support incorporating regional anesthesia into injury treatment protocols. Trauma patients require special considerations to ensure safety, efficacy, and optimal benefit. This article explores current research and future directions for regional anesthesia in trauma care.

Keywords: Analgesia; Injury; Peripheral nerve block; Regional anesthesia; Trauma; Trauma pain.

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Conflict of interest statement

Disclosure Dr R.E. Samet has a consultant relationship with Butterfly Network, LLC. Dr E.B. Powelson, Dr I.R. Slade, and Dr C.R. Parrino have nothing to disclose.

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