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Comment
. 2025 Oct 29:12:1663398.
doi: 10.3389/fvets.2025.1663398. eCollection 2025.

Commentary: Musculoskeletal adverse events in dogs receiving bedinvetmab (Librela)

Affiliations
Comment

Commentary: Musculoskeletal adverse events in dogs receiving bedinvetmab (Librela)

Anthony Simon et al. Front Vet Sci. .
No abstract available

Keywords: Librela; NGF; accelerated joint destruction; bedinvetmab; disproportionality analyses; dog; pharmacovigilance; rapidly progressive osteoarthritis (RPOA).

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Conflict of interest statement

AS, BM, OK, and AW were employed by Zoetis. The authors declare that this study received funding from Zoetis. The funder had the following involvement in the study: review of pharmacovigilance data from cases listed in the case series, writing of this article and the decision to submit it for publication.

Comment on

  • Musculoskeletal adverse events in dogs receiving bedinvetmab (Librela).
    Farrell M, Waibel FWA, Carrera I, Spattini G, Clark L, Adams RJ, Von Pfeil DJF, De Sousa RJR, Villagrà DB, Amengual-Vila M, Paviotti A, Quinn R, Harper J, Clarke SP, Jordan CJ, Hamilton M, Moores AP, Greene MI. Farrell M, et al. Front Vet Sci. 2025 May 9;12:1581490. doi: 10.3389/fvets.2025.1581490. eCollection 2025. Front Vet Sci. 2025. PMID: 40417367 Free PMC article.

References

    1. Farrell M, Waibel FWA, Carrera I, Spattini G, Clark L, Adams RJ, et al. Musculoskeletal adverse events in dogs receiving bedinvetmab (Librela). Front Vet Sci. (2025) 12:1581490. 10.3389/fvets.2025.1581490 - DOI - PMC - PubMed
    1. Simic M, Harmer A, Esch Mvd, Bennell K, Ferreira P, March L, et al. Do non-steroidal anti-inflammatory drugs cause osteoarthritis progression, a systematic review and meta analysis. Osteoarthritis Cartilage. (2019) 27:S280–2. 10.1016/j.joca.2019.02.663 - DOI
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    1. Forestier F. Coxites Rhumatismales Subaigues et Chroniques. Paris: University of Paris; (1957).
    1. Flemming DJ, Gustas-French CN. Rapidly progressive osteoarthritis: a review of the clinical and radiologic presentation. Curr Rheumatol Rep. (2017) 19:42. 10.1007/s11926-017-0665-5 - DOI - PubMed

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