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. 1973 May;24(5):781-9.

The sheep immune response. Variation of anti-hapten and anti-carrier antibodies in the 1 and 2 immunoglobulin fractions

R A Margni, O D Castrelos, C B Paz

The sheep immune response. Variation of anti-hapten and anti-carrier antibodies in the 1 and 2 immunoglobulin fractions

R A Margni et al. Immunology. 1973 May.

Abstract

The results obtained in the quantification of γ1 and γ2 anti-hapten (DNP) and anti-carrier (HGG) antibodies obtained weekly during 50 weeks and proceeding from a group of three Merino sheep immunized with DNP—HGG, are described.

The primary and secondary response and the antibody variations in weekly repeated stimulations were studied.

The anti-DNP and anti-HGG total antibodies have similar variations. γ1 and γ2 anti-DNP and anti-HGG antibodies do not show differences in the primary response nor in weekly repeated stimulations.

In the secondary response, a high increase of γ1 with loss of γ2 is observed. After a certain time γ1 decreases and γ2 increases.

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