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. 1973 Aug 3;181(4098):443-4.
doi: 10.1126/science.181.4098.443.

Superinduction of endogenous type C virus by 5-bromodeoxyuridine from transformed mouse clones

M M Lieber, D M Livingston, G J Todaro

Superinduction of endogenous type C virus by 5-bromodeoxyuridine from transformed mouse clones

M M Lieber et al. Science. .

Abstract

Certain transformed subclones of the mouse cell line BALB/3T3 release 5 to 15 times more type C virus per cell than the parent cell line after treatment with 5-bromodeoxyuridine. Virus release begins within 8 hours and exponentially increases for the first 24 to 48 hours. Superinducibility is associated with the transformed phenotype.

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