A randomized clinical trial of remote Group-Based comprehensive behavioral intervention for tics

Takeshi Inoue¹, Jumpei Iwanami², Chie Kuroiwa², Mio Mizukoshi³, Kohei Togashi⁴, Yuka Hatayama⁵, Akira Nagai⁶, Akemi Tomoda⁷, Douglas W Woods⁸, Hiroshi Ozawa⁹, Kimiko Deguchi¹⁰, Kyoko Hoshino¹¹, Mizuki Kobayashi¹², Maiko Nonaka¹³, Natsumi Matsuda¹⁴, Ryuta Ishii¹⁵, Ryoko Otani², Shinichiro Nagamitsu¹⁶, Tatsuo Fuchigami¹⁷, Tasuku Kitajima², Yukihiko Fujita¹⁸, Yukiko Kano¹⁹, Yoshifumi Mizuno²⁰, Yukifumi Monden¹², Yuichi Suzuki²¹, Ryoichi Sakuta²

Affiliations

¹ Child Development and Psychosomatic Medicine Center, Saitama Medical Center, Dokkyo Medical University, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama, Japan. tinoue@dokkyomed.ac.jp.
² Child Development and Psychosomatic Medicine Center, Saitama Medical Center, Dokkyo Medical University, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama, Japan.
³ The Institute of Clinical Psychology, Bunkyo University, Saitama, Japan.
⁴ Department of Psychology, Temple University Japan Campus, Tokyo, Japan.
⁵ Department of Pediatrics and Adolescent, Tokyo Medical University, Tokyo, Japan.
⁶ Division of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, Japan.
⁷ Research Center for Child Mental Development, University of Fukui, Fukui, Japan.
⁸ Department of Psychology, Loyola University Chicago, Chicago, IL, USA.
⁹ Department of Neuropediatrics, Shimada Ryoiku Medical Center Hachioji for Challenged Children, Tokyo, Japan.
¹⁰ Deguchi Pediatric Clinic, Nagasaki, Japan.
¹¹ Segawa Memorial Neurological Clinic for Children, Tokyo, Japan.
¹² Department of Pediatrics, Jichi Medical University, Tochigi, Japan.
¹³ Department of Psychology, Faculty of Liberal Arts, Teikyo University, Tokyo, Japan.
¹⁴ Department of Developmental Psychology, Shirayuri University, Tokyo, Japan.
¹⁵ Department of Pediatrics and Child Health, Kurume University School of Medicine, Fukuoka, Japan.
¹⁶ Department of Pediatrics, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
¹⁷ Department of Pediatrics, IMS Fujimi General Hospital, Saitama, Japan.
¹⁸ Department of Pediatrics, Ashikaganomori Ashikaga Hospital, Tochigi, Japan.
¹⁹ Department of Child Psychiatry, The University of Tokyo Hospital, Tokyo, Japan.
²⁰ Research Centre for Child Mental Development, University of Fukui, Fukui, Japan.
²¹ Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan.

PMID: 41240071
DOI: 10.1007/s00787-025-02912-5

A randomized clinical trial of remote Group-Based comprehensive behavioral intervention for tics

Takeshi Inoue et al. Eur Child Adolesc Psychiatry. 2025.

. 2025 Nov 15.

doi: 10.1007/s00787-025-02912-5. Online ahead of print.

Authors

Affiliations

¹ Child Development and Psychosomatic Medicine Center, Saitama Medical Center, Dokkyo Medical University, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama, Japan. tinoue@dokkyomed.ac.jp.
² Child Development and Psychosomatic Medicine Center, Saitama Medical Center, Dokkyo Medical University, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama, Japan.
³ The Institute of Clinical Psychology, Bunkyo University, Saitama, Japan.
⁴ Department of Psychology, Temple University Japan Campus, Tokyo, Japan.
⁵ Department of Pediatrics and Adolescent, Tokyo Medical University, Tokyo, Japan.
⁶ Division of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, Japan.
⁷ Research Center for Child Mental Development, University of Fukui, Fukui, Japan.
⁸ Department of Psychology, Loyola University Chicago, Chicago, IL, USA.
⁹ Department of Neuropediatrics, Shimada Ryoiku Medical Center Hachioji for Challenged Children, Tokyo, Japan.
¹⁰ Deguchi Pediatric Clinic, Nagasaki, Japan.
¹¹ Segawa Memorial Neurological Clinic for Children, Tokyo, Japan.
¹² Department of Pediatrics, Jichi Medical University, Tochigi, Japan.
¹³ Department of Psychology, Faculty of Liberal Arts, Teikyo University, Tokyo, Japan.
¹⁴ Department of Developmental Psychology, Shirayuri University, Tokyo, Japan.
¹⁵ Department of Pediatrics and Child Health, Kurume University School of Medicine, Fukuoka, Japan.
¹⁶ Department of Pediatrics, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
¹⁷ Department of Pediatrics, IMS Fujimi General Hospital, Saitama, Japan.
¹⁸ Department of Pediatrics, Ashikaganomori Ashikaga Hospital, Tochigi, Japan.
¹⁹ Department of Child Psychiatry, The University of Tokyo Hospital, Tokyo, Japan.
²⁰ Research Centre for Child Mental Development, University of Fukui, Fukui, Japan.
²¹ Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan.

PMID: 41240071
DOI: 10.1007/s00787-025-02912-5

No abstract available

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Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests.

References

1. Ueda K, Black KJ (2021) A comprehensive review of tic disorders in children. J Clin Med 10(11):2479. https://doi.org/10.3390/jcm10112479 - DOI - PubMed - PMC
1. Knight T, Steeves T, Day L, Lowerison M, Jette N, Pringsheim T (2012) Prevalence of tic disorders: a systematic review and meta-analysis. Pediatr Neurol 47(2):77–90. https://doi.org/10.1016/j.pediatrneurol.2012.05.002 - DOI - PubMed
1. Leckman JF, Zhang H, Vitale A, Lahnin F, Lynch K, Bondi C, Kim YS, Peterson BS (1998) Course of tic severity in tourette syndrome: the first two decades. Pediatrics 102(1):14–19. https://doi.org/10.1542/peds.102.1.14 - DOI - PubMed
1. Pringsheim T, Okun MS, Müller-Vahl K, Martino D, Jankovic J, Cavanna AE, Woods DW, Robinson M, Jarvie E, Roessner V, Oskoui M, Holler-Managan Y, Piacentini J (2019) Practice guideline recommendations summary: treatment of tics in people with tourette syndrome and chronic tic disorders. Neurology 92(19):896–906. https://doi.org/10.1212/WNL.0000000000007466 - DOI - PubMed - PMC
1. Woods DW, Piacentini J, Chang S (2008) Managing tourette syndrome: A behavioral intervention for children and adults therapist guide. Oxford University Press

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A randomized clinical trial of remote Group-Based comprehensive behavioral intervention for tics

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A randomized clinical trial of remote Group-Based comprehensive behavioral intervention for tics

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