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Case Reports
. 2025 Jun 12;1(4):e00027-25.
doi: 10.1128/asmcr.00027-25. eCollection 2025 Jul.

A Haemophilus influenzae-associated mycotic aneurysm months after treated bacteremia

Josiah Bennett  1 , Sarah Lohsen  2 , Elizabeth Y Kim  2 , Pranavi Ravichandran  3 , William Blake  2 , Kimberly A Workowski  2 , Sarah W Satola  2   4 , Matthew H Collins  2 , Danielle B Steed  2
Affiliations
Case Reports

A Haemophilus influenzae-associated mycotic aneurysm months after treated bacteremia

Josiah Bennett et al. ASM Case Rep. .

Abstract

Background: Invasive nontypeable Haemophilus influenzae (NTHi) infections increased dramatically in the Atlanta area in 2017-2018. Most isolates from these infections belonged to two closely related genetic lineages and were likely being spread through sexual networks of men living with HIV.

Case summary: We present a case of a 63-year-old male with well-controlled HIV and treated NTHi pericarditis and bacteremia who we diagnosed with an infected right superficial femoral artery pseudoaneurysm due to NTHi. The causative strain belonged to one of the lineages identified in the 2017-2018 case clusters.

Conclusion: This case illustrates that novel disease phenotypes continue to emerge for unusually pathogenic strains of NTHi.

Keywords: HIV; invasive infection; mycotic aneurysm; nontypeable Haemophilus influenzae.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig 1
Fig 1
Ultrasound of the right superficial femoral artery. The images show representative longitudinal views of the vessel (A) without Doppler and (B) with Doppler. Yellow arrows indicate the pseudoaneurysm.
Fig 2
Fig 2
The patient’s initial computed tomographic scan showing the pseudoaneurysm of the right superficial femoral artery (yellow arrows) on representative axial (A), sagittal (B), and coronal (C) views.
See this image and copyright information in PMC

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