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. 1977 Aug-Sep;34(7 Suppl):CLIV-CLXIV.

[Endocrine sequela of radiation treatment of extracranial head and neck tumors]

[Article in French]
P Czernichow, O Cachin, R Rappaport, F Flamant, D Sarrazin, O Schweisguth
  • PMID: 412481

[Endocrine sequela of radiation treatment of extracranial head and neck tumors]

[Article in French]
P Czernichow et al. Arch Fr Pediatr. 1977 Aug-Sep.

Abstract

A study of the thyroid and hypothalamo-pituitary functions was undertaken in 14 children having been irradiated for tumors of the neck and head. The following anomalies were found: S.T.H. deficiency: 8 cases, A.C.T.H. deficiency: 2 cases, T.S.H. deficiency: 4 cases, primary thyroid insufficiency: 4 cases. Growth was severely impaired since the height of 10 out of 14 patients was less than or equal to 2 S.D. These results emphasize the frequency of endocrine lesions related to radiotherapy, as the lesions were essentially extracranial. They also show a repercussion on growth, which worsen the long-term prognosis of these diseases.

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