Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Nov 18;13(11):e71491.
doi: 10.1002/ccr3.71491. eCollection 2025 Nov.

Chilaiditi's Syndrome: An Unusual Cause of Acute Respiratory Distress

Affiliations

Chilaiditi's Syndrome: An Unusual Cause of Acute Respiratory Distress

Prosper Adjei et al. Clin Case Rep. .

Abstract

Chilaiditi's syndrome is characterized by hepatodiaphragmatic interposition of the bowel, usually colon, with associated symptoms. Occasionally, affected individuals may experience acute respiratory distress and retrosternal pain which can mimic life-threatening conditions like pulmonary embolism and myocardial infarction. This case report underscores the need for clinicians to be aware of this rare syndrome as it is amenable to conservative treatment in most instances.

Keywords: Chilaiditi's sign; Chilaiditi's syndrome; respiratory distress; shortness of breath.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Resting 12‐lead ECG showing normal sinus rhythm with no ST‐segment or T wave changes.
FIGURE 2
FIGURE 2
Posteroanterior chest x‐ray showing elevation of the right hemidiaphragm (yellow arrow) and a large volume of air with haustral folds (red arrow) below the diaphragm.
FIGURE 3
FIGURE 3
A repeat posteroanterior chest x‐ray showing complete resolution of the air under the right hemidiaphragm.

References

    1. Silva F. S., Moutinho J., Vasconcelos T., and Simões I. G., “Chilaiditi Syndrome: A Rare Case and Clinical Insights for Diagnosis and Management,” Cureus 15 (2023): e48932. - PMC - PubMed
    1. Caicedo L., Wasuwanich P., Rivera A., Lopez M. S., and Karnsakul W., “Chilaiditi Syndrome in Pediatric Patients ‐ Symptomatic Hepatodiaphragmatic Interposition of Colon: A Case Report and Review of Literature,” World Journal of Clinical Pediatrics 10 (2021): 40–47. - PMC - PubMed
    1. Ben Ismail I., Zenaidi H., Rebii S., Yahmadi A., and Zoghlami A., “Chilaiditi's Sign: A Rare Differential Diagnosis of Pneumoperitoneum,” Clinical Case Reports 8 (2020): 3101–3103. - PMC - PubMed
    1. Adjei P., Asamoah P. H., Ohene D. A., Amoakohene‐Yeboah A., and Asasu S. A., “Chilaiditi's Sign: A Rare Finding in a Patient With Concurrent Liver Cirrhosis and Chronic Lymphocytic Leukemia,” Clinical Medicine Insights: Case Reports 17 (2024): 11795476241278973. - PMC - PubMed
    1. Chilaiditi D., “On the Question of Hepatoptosis Ptosis and Generally in the Exclusion of Three Cases of Temporary Partial Liver Displacement,” Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin 11 (1910): 173–208.

LinkOut - more resources