Age-Adjusted Cystatin C Z-Scores in Neonates and Infants

Guido Filler^{1

2

3

4}, Mashael Abujabal^{1

5}, Ajay Parkash Sharma^{1

4}, Joanne Grimmer¹, Amrit Kirpalani^{1

4}, Maria Esther Díaz González de Ferris⁶

Affiliations

¹ Department of Paediatrics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
² Department of Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
³ Lilibeth Caberto Kidney Clinical Research Unit, London Health Sciences Centre, London, Ontario, Canada.
⁴ Children's Health Research Institute, University of Western Ontario, London, Ontario, Canada.
⁵ Department of Pediatrics, East Jeddah General Hospital, Ministry of Health, Jeddah, Saudi Arabia.
⁶ Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Guido Filler et al. Kidney Int Rep. 2025.

. 2025 Sep 4;10(11):4087-4089.

doi: 10.1016/j.ekir.2025.09.008. eCollection 2025 Nov.

Guido Filler^{1

2

3

4}, Mashael Abujabal^{1

5}, Ajay Parkash Sharma^{1

4}, Joanne Grimmer¹, Amrit Kirpalani^{1

4}, Maria Esther Díaz González de Ferris⁶

¹ Department of Paediatrics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
² Department of Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
³ Lilibeth Caberto Kidney Clinical Research Unit, London Health Sciences Centre, London, Ontario, Canada.
⁴ Children's Health Research Institute, University of Western Ontario, London, Ontario, Canada.
⁵ Department of Pediatrics, East Jeddah General Hospital, Ministry of Health, Jeddah, Saudi Arabia.
⁶ Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

No abstract available

Figures

1. Filler G., Sharma A.P., Exantus J. GFR and eGFR in term-born neonates. J Am Soc Nephrol. 2022;33:1229–1231. doi: 10.1681/ASN.2022040470. - DOI - PMC - PubMed
1. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl. 2012;2:1–138.
1. Filler G., Bhayana V., Schott C., Díaz-González De Ferris M.E. How should we assess renal function in neonates and infants? Acta Paediatr. 2021;110:773–780. doi: 10.1111/apa.15557. - DOI - PubMed
1. Bariciak E., Yasin A., Harrold J., Walker M., Lepage N., Filler G. Preliminary reference intervals for cystatin C and beta-trace protein in preterm and term neonates. Clin Biochem. 2011;44:1156–1159. doi: 10.1016/j.clinbiochem.2011.06.987. - DOI - PubMed
1. Filler G., Lepage N. Should the Schwartz formula for estimation of GFR be replaced by cystatin C formula? Pediatr Nephrol. 2003;18:981–985. doi: 10.1007/s00467-003-1271-5. - DOI - PubMed