Induction of hepatitis B antibody in experimental animals by immunization with A-2 plaque virus
- PMID: 4128387
- PMCID: PMC356803
- DOI: 10.1128/JVI.12.6.1598-1607.1973
Induction of hepatitis B antibody in experimental animals by immunization with A-2 plaque virus
Abstract
A sero-conversion for hepatitis B antibody has resulted from immunization of patas monkeys, guinea pigs, and rabbits with the A-2 plaque virus. This agent was isolated in tissue culture from patient sera that were positive for hepatitis B antigen. The immune response was assayed with techniques of direct and indirect counter-immunoelectrophoresis, and immune electron microscopy.
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