Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Dec;106(6):e70487.
doi: 10.1111/tan.70487.

The Novel HLA-B*15:751 Allele Identified Through Next Generation Sequencing in an Individual From Tamil Nadu, India

Affiliations

The Novel HLA-B*15:751 Allele Identified Through Next Generation Sequencing in an Individual From Tamil Nadu, India

Meshach Paul D et al. HLA. 2025 Dec.

Abstract

HLA-B*15:751 differs from HLA-B*15:02:01:01 by a single nucleotide in exon 3, changing residue 103 from Valine to Leucine.

Keywords: HLA‐B*15; NGS; high resolution HLA typing; novel HLA‐B allele; sequence based typing.

PubMed Disclaimer

References

    1. T. Shiina, K. Hosomichi, H. Inoko, and J. K. Kulski, “The HLA Genomic Loci Map: Expression, Interaction, Diversity and Disease,” Journal of Human Genetics 54, no. 1 (2009): 15–39, https://doi.org/10.1038/jhg.2008.5.
    1. A. M. Little and P. Parham, “Polymorphism and Evolution of HLA Class I and II Genes and Molecules,” Reviews in Immunogenetics 1, no. 1 (1999): 105–123.
    1. D. J. Barker, G. Maccari, X. Georgiou, et al., “IPD‐IMGT/HLA Database,” Nucleic Acids Research 51 (2023): D1053–D1060.
    1. S. G. E. Marsh, E. D. Albert, W. F. Bodmer, et al., “Nomenclature for Factors of the HLA System, 2010,” Tissue Antigens 75, no. 4 (2010): 291–455, https://doi.org/10.1111/j.1399‐0039.2010.01466.x.

Substances

LinkOut - more resources