Toward Inclusive, Evidence-Based rTMS Care for Patients With Co-Occurring Substance Use Disorders

Vaughn R Steele^{1

2}, Merideth A Addicott³, Giovanni Addolorato^{4

5}, Travis Baker⁶, Kathryn Biernacki⁷, Antonello Bonci^{8

9}, Kathleen T Brady^{10

11}, Stacey B Daughters¹², Marco Diana¹³, Timothy C Durazzo^{14

15}, Hamed Ekhtiari¹⁶, Shirley Fecteau^{17

18}, Samantha J Fede¹⁹, Brett Froeliger²⁰, Luigi Gallimberti²¹, Eduardo A Garza-Villarreal²², Tony P George²³, Anna E Goudriaan²⁴, Markus Heilig²⁵, Dongyu Kang², Tonisha E Kearney-Ramos²⁶, Xingbao Li¹⁰, Joshua A Lile²⁷, Graziella Madeo⁹, Michelle Madore^{14

28}, Diana Martinez^{29

30}, Giovanni Maretinotti³¹, Daniel M McCalley¹⁴, Scott J Moeller³², Chiara Montemitro²⁵, Claudia B Padula^{28

29}, Nicole Petersen³³, Mauro Pettorruso³¹, Noah S Philip^{34

35}, Gopalkumar Rakesh²⁸, Betty Jo Salmeron⁷, Gregory L Sahlem²⁶, Angela Sanna³⁶, Christian G Schütz^{37

38}, Arnt Schellekens^{39

40}, Christine E Sheffer⁴¹, Ghazaleh Soleimani¹⁶, Primavera A Spagnolo⁴², Elliot A Stein⁷, Madhukar Trivedi⁴³, Heather Burrell Ward⁴⁴, Michael J Wesley²⁸, Jonathan R Young^{26

45}, Kai Yuan⁴⁶, Tifei Yuan⁴⁷, Abraham Zangen⁴⁸, Di Zhao⁴⁹, Min Zhao⁴⁹, Colleen A Hanlon^{50

51}

Affiliations

¹ Yale University, New Haven.
² Hartford Hospital, Hartford, CT.
³ Wake Forest University, Winston-Salem, NC.
⁴ Catholic University of Rome, Rome.
⁵ Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome.
⁶ Rutgers University, New Brunswick, NJ.
⁷ National Institute on Drug Abuse-Intramural Program, Baltimore, MD.
⁸ Global Institute of Addictions, Miami.
⁹ Brain & Care, Rimini, Italy.
¹⁰ Medical University of South Carolina, Charleston, SC.
¹¹ South Carolina Clinical and Translational Research Institute, Charleston, SC.
¹² University of North Carolina at Chapel Hill, Chapel Hill, NC.
¹³ University of Sassari, Sassari, Italy.
¹⁴ Stanford University School of Medicine, Stanford.
¹⁵ Palo Alto Veterans Administration Health Care System, Palo Alto, CA.
¹⁶ University of Minnesota, Minneapolis, MN.
¹⁷ Université Laval, Quebec City, QC.
¹⁸ CERVO Brain Research Centre, Quebec City, QC.
¹⁹ Auburn University, Auburn, AL.
²⁰ University of Missouri, Columbia, MO.
²¹ Novella Fronda Foundation, Padua, Italy.
²² Universidad Nacional Autónoma de México Juriquilla, Querétaro, Mexico.
²³ University of Toronto, Toronto.
²⁴ University of Amsterdam, Amsterdam.
²⁵ Linköping University, Linköping, Sweden.
²⁶ Duke University School of Medicine, Durham, NC.
²⁷ University of Kentucky College of Medicine, Lexington, KY.
²⁸ VA Palo Alto Health Care System, Palo Alto, CA.
²⁹ New York State Psychiatric Institute, New York.
³⁰ Columbia University Irving Medical Center, New York.
³¹ University G. d'Annunzio of Chieti, Chieti, Italy.
³² Renaissance School of Medicine at Stony Brook University, Stony Brook, NY.
³³ University of California Los Angeles, Los Angeles.
³⁴ Brown University, Providence, RI.
³⁵ VA Providence Healthcare System, Providence, RI.
³⁶ SS Trinita' Hospital, Cagliari, Italy.
³⁷ University of British Columbia, Vancouver.
³⁸ Djavad Mowafaghian Centre for Brain Health, Vancouver.
³⁹ Radboud University Medical Center, Nijmegen, Netherlands.
⁴⁰ Nijmegen Institute for Scientist Practitioners in Addictions, Nijmegen, Netherlands.
⁴¹ Roswell Park Comprehensive Cancer Center, Buffalo, NY.
⁴² Harvard Medical School, Boston.
⁴³ University of Texas Southwestern, Dallas.
⁴⁴ Vanderbilt University Medical Center, Nashville, TN.
⁴⁵ Durham VA Health Care System, Durham, NC.
⁴⁶ Xidian University, Xi'An, China.
⁴⁷ Shanghai Jiaotong University, Shanghai, China.
⁴⁸ Zelman Center for Neuroscience, Be'er Sheva, Israel.
⁴⁹ Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁵⁰ Wake Forest University School of Medicine, Winston-Salem, NC.
⁵¹ BrainsWay, Burlington, MA.

PMID: 41320823
DOI: 10.1176/appi.ajp.20250407

Toward Inclusive, Evidence-Based rTMS Care for Patients With Co-Occurring Substance Use Disorders

Vaughn R Steele et al. Am J Psychiatry. 2025.

. 2025 Dec 1;182(12):1095-1096.

doi: 10.1176/appi.ajp.20250407. Epub 2025 Dec 1.

Authors

Affiliations

¹ Yale University, New Haven.
² Hartford Hospital, Hartford, CT.
³ Wake Forest University, Winston-Salem, NC.
⁴ Catholic University of Rome, Rome.
⁵ Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome.
⁶ Rutgers University, New Brunswick, NJ.
⁷ National Institute on Drug Abuse-Intramural Program, Baltimore, MD.
⁸ Global Institute of Addictions, Miami.
⁹ Brain & Care, Rimini, Italy.
¹⁰ Medical University of South Carolina, Charleston, SC.
¹¹ South Carolina Clinical and Translational Research Institute, Charleston, SC.
¹² University of North Carolina at Chapel Hill, Chapel Hill, NC.
¹³ University of Sassari, Sassari, Italy.
¹⁴ Stanford University School of Medicine, Stanford.
¹⁵ Palo Alto Veterans Administration Health Care System, Palo Alto, CA.
¹⁶ University of Minnesota, Minneapolis, MN.
¹⁷ Université Laval, Quebec City, QC.
¹⁸ CERVO Brain Research Centre, Quebec City, QC.
¹⁹ Auburn University, Auburn, AL.
²⁰ University of Missouri, Columbia, MO.
²¹ Novella Fronda Foundation, Padua, Italy.
²² Universidad Nacional Autónoma de México Juriquilla, Querétaro, Mexico.
²³ University of Toronto, Toronto.
²⁴ University of Amsterdam, Amsterdam.
²⁵ Linköping University, Linköping, Sweden.
²⁶ Duke University School of Medicine, Durham, NC.
²⁷ University of Kentucky College of Medicine, Lexington, KY.
²⁸ VA Palo Alto Health Care System, Palo Alto, CA.
²⁹ New York State Psychiatric Institute, New York.
³⁰ Columbia University Irving Medical Center, New York.
³¹ University G. d'Annunzio of Chieti, Chieti, Italy.
³² Renaissance School of Medicine at Stony Brook University, Stony Brook, NY.
³³ University of California Los Angeles, Los Angeles.
³⁴ Brown University, Providence, RI.
³⁵ VA Providence Healthcare System, Providence, RI.
³⁶ SS Trinita' Hospital, Cagliari, Italy.
³⁷ University of British Columbia, Vancouver.
³⁸ Djavad Mowafaghian Centre for Brain Health, Vancouver.
³⁹ Radboud University Medical Center, Nijmegen, Netherlands.
⁴⁰ Nijmegen Institute for Scientist Practitioners in Addictions, Nijmegen, Netherlands.
⁴¹ Roswell Park Comprehensive Cancer Center, Buffalo, NY.
⁴² Harvard Medical School, Boston.
⁴³ University of Texas Southwestern, Dallas.
⁴⁴ Vanderbilt University Medical Center, Nashville, TN.
⁴⁵ Durham VA Health Care System, Durham, NC.
⁴⁶ Xidian University, Xi'An, China.
⁴⁷ Shanghai Jiaotong University, Shanghai, China.
⁴⁸ Zelman Center for Neuroscience, Be'er Sheva, Israel.
⁴⁹ Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁵⁰ Wake Forest University School of Medicine, Winston-Salem, NC.
⁵¹ BrainsWay, Burlington, MA.

PMID: 41320823
DOI: 10.1176/appi.ajp.20250407

No abstract available

Keywords: Addiction Psychiatry; Neurostimulation; TMS.

PubMed Disclaimer

Conflict of interest statement

Dr. Hanlon has received research support from National Institute of Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism. She has acted as a consultant for Magstim and Brainsway, and has equity in BrainsWay. Dr. Heilig has received compensation from Aelis Farma, BrainsWay, Camurus, Indivior, Janssen, Lundbeck, and Molteni. Dr. Philip has served on the scientific advisory board of Pulvinar Neuro, and has acted as a consultant for Motif Neurotech. Dr, Sahlem has collaborated with MagVenture and MECTA as part of investigator-initiated trials, has acted as a consultant for and has equity in Trial Catalyst, LLC, and has acted as a consultant for Indivior. Prof. Zangen is a co-inventor of Deep TMS coils and has financial interest in BrainsWay. Dr. Soleimani has received funding from MnDrive. Dr. Spagnolo has received funding from Walgreens Boots Alliance. Dr. Trivedi has acted as a consultant for Acadia Pharmaceuticals, Alkermes Inc., Alto Neuroscience Inc., Axsome Therapeutics, BasePoint Health Management LLC, Biogen MA Inc., Cerebral Inc., Circular Genomics Inc., Compass Pathfinder Limited, Daiichi Sankyo Inc., GH Research, GreenLight VitalSign6 Inc., Heading Health, Janssen Pharmaceutical, Legion Health, Merck Sharp & Dohme Corp., Mind Medicine Inc., Myriad Neuroscience, Naki Health Ltd., Neurocrine Biosciences Inc., Noema Pharma AG, Orexo US Inc., Otsuka America Pharmaceutical Inc., Otsuka Europe LTD, Otsuka Pharmaceutical Development & Commercialization Inc., Praxis Precision Medicines Inc., PureTech LYT Inc, Relmada Therapeutics Inc., SAGE Therapeutics, Seaport Therapeutics Inc., Signant Health, Sparian Biosciences, Titan Pharmaceuticals, Takeda Pharmaceuticals Inc., and WebMD. He has received grant/research funding from NIMH, NIDA, NCATS, American Foundation for Suicide Prevention, Patient-Centered Outcomes Research Institute (PCORI), Blue Cross Blue Shield of Texas, SAMHSA, and the DoD. Additionally, he has received editorial compensation from Elsevier and Oxford University Press. Dr. Young has received funding from the U.S. Department of Veterans Affairs (VA) Clinical Science Research and Development Service Career Development Award (CDA-2: 1IK2CX002610-01); the VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC) at the Durham VA Health Care System; the Department of Psychiatry & Behavioral Sciences at Duke University; and Bass Connections at Duke University. Dr. Young has received industry support in the form of device donations from Brain Ultimate, Inc. and holds equity interest in Synaptiq Neurotech, Inc. and Synaptiq Psychiatry, PLLC. The other authors report no financial relationships with commercial interests.

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Toward Inclusive, Evidence-Based rTMS Care for Patients With Co-Occurring Substance Use Disorders

Affiliations

Toward Inclusive, Evidence-Based rTMS Care for Patients With Co-Occurring Substance Use Disorders

Authors

Affiliations

Conflict of interest statement

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LinkOut - more resources

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