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. 2026 Jan 1;32(1S Suppl 1):S28-S35.
doi: 10.1097/RHU.0000000000002301. Epub 2025 Dec 8.

Barriers and Facilitators Associated With Delays in the Diagnosis and Treatment of Lupus: Insights From Patients and Rheumatologists From the Andean/Bolivarian Region

Ana Ospina-Caicedo  1   2 , Yurilis Fuentes-Silva  3 , Kelly Escobar-Jimenez  4 , Romina Payan-Castillejos  5 , Manuel Ugarte-Gil  6   7 , Patricia E Díaz-Cuiza  8 , Sergio Guevara-Pacheco  9 , Iván Stekman  10 , Amaranta Manrique de Lara  11 , Ivonne Del Cisne Quezada-López  12 , Edgar A Castro-Franco  13 , Jesús G Ballesteros  14 , Irama Maldonado  15 , Gloria Vázquez  16 , Sandra Y Martinez-Gomez  13 , María Del Carmen Ochoa  17 , Carlota Acosta  15 , Jorge H Izquierdo  18 , Ericka V Sarabia-Chavez  19 , Nataly Liduvina Beleño-Epieyu  20 , Cecilia Camacho  21 , Luisa Ortega-Latan  15 , Carolina Espinosa-Escobar  22 , Tirsa Colmenares-Roa  23 , Danith Medina-Bornachera  24 , Keisy Orduz-Uribe  25 , Alexander Serna-Paz  26 , Jennyffer Vélez-Martínez  27 , Marylin Parra-Martínez  28 , Rómulo Villacís-Tamayo  29 , Susana Lucero Revollo  30 , Juan P Gómez-Alconz  31 , Rosana Quintana  32 , Ingris Del Pilar Peláez-Ballestas  33
Affiliations

Barriers and Facilitators Associated With Delays in the Diagnosis and Treatment of Lupus: Insights From Patients and Rheumatologists From the Andean/Bolivarian Region

Ana Ospina-Caicedo et al. J Clin Rheumatol. .

Abstract

Abstract: Systemic lupus erythematosus (SLE) is difficult to diagnose and treat due to its heterogeneity. In the Andean/Bolivarian Region (comprising Bolivia, Colombia, Ecuador, Peru, and Venezuela), fragmented health care systems, limited access to specialists, and social inequities further exacerbate these challenges.

Objective: To examine the barriers and facilitators contributing to delays in the diagnosis and treatment of SLE from the perspectives of patients and rheumatologists.

Methods: Qualitative study conducted between January 2024 and April 2025, comprising interviews with 59 patients and focus groups with 76 rheumatologists across five countries. Data were thematically analyzed using the World Health Organization (WHO) right-to-health framework (availability, accessibility, acceptability, quality) and emerging themes.

Results: Seven major themes influence delay. Availability: shortages of rheumatologists, laboratory tests, and medications. Accessibility: stigma, geographic, cultural, and socioeconomic barriers, as well as self-medication. Acceptability: gender bias and lack of provider sensitivity. Quality: inadequate training in primary care, poor coordination, fragmented care, and excessive bureaucracy. Disease characteristics: heterogeneity and severity. Migration: cross-border mobility facilitated access to medications but introduced new barriers. Finally, health inequity is an overarching theme that explains delay. Facilitators included rheumatology training, multidisciplinary care, and public health coverage.

Conclusions: Delays in SLE care reflect limitations within the health system, social stigma, and inequities. Strengthening primary care training, streamlining administrative processes, and fostering patient-centered, multidisciplinary approaches are critical. In addition, regional and transnational health policies are needed to guarantee timely and equitable access to diagnosis and treatment of SLE.

Keywords: Andean/Bolivarian Region; barriers and facilitators; delay; qualitative research; systemic lupus erythematosus.

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Conflict of interest statement

The authors declare no conflict of interest.

References

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